The Inspectorate of Government is currently headed by Ms. Irene Mulyagonja as Inspector General of Government following her appointment by the President with the approval of the Parliament of Uganda.

As the head of the institution, she provides guidance on the functioning of the office and therefore, authorizes and supervises investigations of cases of corruption, issues reports of investigations, issues bank inspection orders, issues witness summons, issues warrants of arrest, authorizes prosecutions, issues orders/directives in the course or as a consequence of investigations, issues IG Parliamentary Reports among other activities.

Mr. George Bamugemereire is Deputy Inspector General of Government following his appointment by the President with the approval of the Parliament of Uganda.

Ms. Mariam Wangadya is Deputy Inspector General of Government following her appointment by the President with the approval of the Parliament of Uganda.

Mrs. Rose N. Kafeero is the Secretary to the Inspectorate of Government (the Accounting Officer). As the head of finance and administration, she provides policy direction for the Inspectorate of Government, ensures budget and budgetary control, provides effective coordination of the activities of the office and manages and coordinates the administrative matters of the Institution.

Mr. Magezi Joram is the Director of Special Investigations. The Directorate is responsible for investigating high profile corruption cases and bringing to book the suspected culprits.

Ms. Sarah Birungi is the Director of Legal Affairs and is responsible for ensuring that the Inspectorate of Government executes its functions and exercises its powers in accordance with the law by rendering legal advice.
She is in charge of addressing issues of maladministration in public offices through handling of complaints involving administrative injustice. She is also responsible for enhancing transparency and accountability in public offices through prosecution of suspects of corruption and abuse of office.

Mr. Rwereeza Jossy Jules is the Director of Education and Prevention of Corruption. He is responsible for stimulating public awareness about the values of Constitutionalism and the activities of the Inspectorate of Government through workshops/seminars, radios and TV programmes, articles in the print media and other means the Inspectorate considers appropriate.

Ms. Twine Annet Kyakunda is the Director of Leadership Code and is responsible for ensuring that the principles and values of integrity, transparency and accountability among leaders in public institutions as specified in the Leadership Code Act are adhered to.
This is done by ensuring that the leaders declare their income, assets and liabilities. The Directorate also investigates leaders who engage in conduct prohibited by the Leadership Code of Conduct in addition to verification of leaders' declarations.

Mr. Muhairwe Polly is the Director of Regional Offices and is responsible for improvement of efficiency of the Inspectorate in service delivery by taking the services of the Inspectorate of Government nearer to the people and ensuring that the Inspectorate's recommendations, directives and orders are implemented by the public officials/institutions.
The Directorate coordinates Regional Offices and provides statistical information on the output of the Inspectorate of Government.

Mr. David Makumbi is the Director of Ombudsman Affairs and is responsible for ensuring that the rule of law and good governance are maintained by public officers through investigation of administrative practices of public officers.
The Directorate is also tasked with carrying out systems studies in various Government Departments and Institutions which are continuously complained about by the general public, with a view of identifying long term solutions to systemic bad governance or disrespect for the rule of law in problematic institutions with a view to identify weak areas that may be conducive to corruption.